Large-volume multi-tined expandable RF ablation in pig livers: comparison of 2D and volumetric measurements of the ablation zone

To compare two-dimensional (2D) and three-dimensional (3D) computed tomography (CT) measurements of ablation zones (AZs) related to the shaft of two different large-volume monopolar multi-tined expandable electrodes.

Methods

Percutaneous radiofrequency (RF) ablation was performed in 12 pigs (81.6 ± 7.8 kg) using two electrodes (LeVeen 5 cm, Rita XL 5 cm; n = 6 in each group). Contrast-enhanced CT with the electrode shaft in place evaluated the AZ. The largest sphere centred on the electrode shaft within the AZ was calculated (1) based on the 2D axial CT image in the plane of the shaft assuming rotational symmetry of the AZ and (2) using prototype software and the 3D volume data of the AZ measured with CT.

Results

The mean largest diameter of a sphere centred on the electrode shaft was always smaller using the 3D data of the AZ than using 2D CT measurements assuming rotational symmetry of the AZ (3D vs 2D): LeVeen 18.2 ± 4.8 mm; 24.5 ± 3.1 mm; p = 0.001; Rita XL 20.0 ± 3.7 mm; 28.8 ± 4.9 mm; p = 0.0002. All AZ showed indentations around the tines.

Conclusions

Two-dimensional CT measurements assuming rotational symmetry of the AZ overestimate the largest ablated sphere centred on the electrode shaft compared with 3D CT measurements.

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Author information

Authors and Affiliations

  1. Department of Radiology, University of Cologne, Joseph-Stelzmann-Str. 9, 50931, Cologne, Germany Christopher Bangard, Silvia Rösgen & Klaus J. Lackner
  2. Department of Visceral and Vascular Surgery, University of Cologne, Joseph-Stelzmann-Str. 9, 50931, Cologne, Germany Roger Wahba & Dirk L. Stippel
  3. Philips Forschungslaboratorien, Hamburg, Germany Rafael Wiemker
  4. Institute of Medical Statistics, Informatics and Epidemiology, University of Cologne, Joseph-Stelzmann-Str. 9, 50931, Cologne, Germany Martin Hellmich
  5. Institute of Experimental Medicine, University of Cologne, Joseph-Stelzmann-Str. 9, 50931, Cologne, Germany Hannah Reiter & Jürgen H. Fischer
  1. Christopher Bangard